About
A research tracker for GLP-1 medications and addiction
GLP-1Addiction.com is dedicated to one question: what the clinical evidence actually shows about GLP-1 receptor agonists and cravings for alcohol, nicotine, opioids and other substances. It is written for people who want the studies, not the headlines.
What the site covers
Emerging clinical evidence suggests GLP-1 receptor agonists may affect cravings, and that evidence arrives as a stream of trials, cohort analyses, preclinical work and press releases of very different quality. We track every trial, every study and every data point so you don't have to sort signal from noise. Each substance has its own section, and a brain-science section explains the shared reward circuitry that makes the research plausible in the first place.
- Alcohol
- Nicotine
- Opioids
- Cannabis
- Gambling
- Brain science and mechanisms
Research decoded, no hype
Our editorial standard is stated on the home page: research-first, source-cited, no hype. Every figure we publish is tied to a named study, and we say when a result is preclinical, when it comes from a rodent model, and when it is a secondary finding pulled from a trial designed to test something else. We also keep a chronological timeline of the key studies so the whole field can be read in order.
One point the site repeats deliberately: GLP-1 medications are not approved for addiction, yet. Reporting on a promising trial is not the same as recommending a treatment, and nothing here should be read as medical advice. The information on this website is for general informational and educational purposes only.
The Signal
The Signal is the blog, where new studies are broken down as they are published, from the first randomized trial of semaglutide for alcohol use disorder to the question of why some people lose cravings and others don't, to what addiction doctors wish patients knew about these drugs. It is where the running story of the field is kept, and it is the best place to start if you are new to the subject.
The provider directory
Alongside the research, we maintain a directory of telehealth providers that prescribe GLP-1 medications, with a Find a Provider tool for people who want to explore treatment options with a clinician. The directory is kept separate from the research pages, and we only feature providers we believe to be reputable. Whether a GLP-1 medication is appropriate for you is a decision for a prescriber who knows your history, not for a website.
Contact
Corrections, missed studies and questions about the site can be sent through the contact page. Because the science is moving quickly, we would rather be told about a new trial the day it appears than find it a month later.